16 Serious Health Conditions Linked Directly To Constantly Being Stressed Out
Stress can make you sick if you let it get the best of you.

The state of the world this year has led to a lot of people being under immense stress. And while stress is never very pleasant, it can also be dangerous to our health. The effects of stress impact our bodies in many ways, and can even kill us if we don’t find ways to manage it and get it under control.
When it comes to how stress affects your health, it can end up wreaking havoc on all the systems in your body. “Your first response to stress is the activation of the autonomic nervous system,” says Dr. Jessica Wright, owner and operator of Rejuvenate Med Spa. “The hypothalamus tells the adrenals to release cortisol and adrenaline.”
These hormones increase your heart rate and, in turn, your cardiac output. You're then able to fight or run from danger. Adds Dr. Wright, “Your hypothalamus cannot tell the difference between perceived threats or real threats.”
But what is cortisol, and why is it important to our health? Says Dr. Wright, “It is our own built-in anti-inflammatory agent.” Sounds perfect, right? Unfortunately, the old saying, “Too much of a good thing,” really holds true here. “One of the ways cortisol cools the body down is by dampening the immune system. Too much cortisol can leave our immune systems vulnerable to pathogens. Our bodies do their absolute best to correct all these issues internally. Chronic stress leading to low cortisol can leave you exhausted and never rested.”
Here are 16 serious health conditions linked directly to constantly being stressed out:
1. Dry eyes
Stress may be linked directly to dry eyes. According to Dr. Leigh Plowman, an optometrist and founder of Dry Eye Directory, “A Korean study found that dry eye disease was more prevalent with increased stress.”
Why? This may be due to increased awareness of pain, increased systemic inflammation in the body due to stress or depression, which can increase the risk of dry eyes.
Adds Dr. Plowman, “People with poorer sleep quality tend to have a higher risk for dry eyes. Sleep deprivation can reduce the quality of the tear film.” Stress may also interrupt the normal blink frequency and quality, leading to increased evaporation and poorer tear quality.
2. Heart disease
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Heart disease is no joke, and stress can directly impact our hearts in a few ways. “Stress can directly increase heart rate and blood flow, and causes the release of cholesterol and triglycerides into the bloodstream,” warns Dr. Chris Norris, a chartered physiotherapist and neurologist with board certification in sleep medicine.
It's also possible that stress is related to other problems — an increased likelihood of smoking, or obesity — that indirectly increase heart risks. Emotional stress can be a trigger for serious cardiac problems, including heart attacks.
3. Sleep disorders
Chronic stress can interfere with sleep, leading to restless nights and decreasing the quality of rest.
“[Stress] leads to either a continually elevated cortisol level, or a continually suppressed level,” says Dr. Bonnie Gasquet, medical director of Wellness Jar Medical Spa. “Either way, your cortisol levels never 'reset' under chronic stress. The natural course of life is that when we go to sleep, cortisol is lowered and melatonin rises to promote sleep. As you can see, the cascade being disrupted, even in this one area, can start you on the path to poor sleep by default."
4. Asthma
Stress can worsen asthma symptoms. These symptoms include shortness of breath, coughing, and wheezing. These symptoms can also indicate several common illnesses. Therefore, the last thing you want is to exhibit symptoms of one illness, misinterpret it as another, while the underlying cause is simply stress.
“Stress triggers the immune system and aggravates the release of certain hormones. This can result in inflammation within the airways of the lungs, triggering an asthma attack,” Dr. Norris reveals.
5. Hair loss
Ever say you're so stressed by something that you begin to tear out your hair? Well, that can be true in a non-literal way.
Says board-certified dermatologist, Dr. Michelle Henry, “Hair loss usually occurs within three months of a stressful event — in this case, the pandemic — so we are right around the time where you may start to notice increased hair loss. Of course, we need to check for other potential triggers before making a diagnosis, but I’ve seen more and more patients looking for solutions for hair loss right now.”
6. Skin breakouts
Your oil glands are directly affected by cortisol, which is your body’s stress hormone. Research reveals that when you’re stressed, your sebum production may go out of balance.
“An imbalance of oil production is often an underlying cause of breakouts. The problem is that people often try to remedy the oil imbalance without considering what’s causing it: stress,” asserts Caleb Backe, health and wellness expert for Maple Holistics.
7. Gum disease
Stress can exacerbate periodontal (gum) disease. This is not typically a hot topic, especially compared to heart disease, but it's an extremely important one to keep in mind.
“The mouth is the gateway to our bodies, and the bacteria located there have a prime opportunity to travel throughout the body and increase inflammation,” says Elliot Reimers, certified nutrition coach at Rave Reviews.
“Inflammation is a fancy word for specialized white blood cells that help fight infection and clean up dangerous debris (think: plaque in the arteries). Out-of-control inflammation is an exaggerated immune response that is disproportionate to the provoking mechanism. It's this out-of-control inflammation that damages gum tissue and bone levels around the teeth that we see with periodontal disease (and consequently damages arteries to promote plaque formation),” Reimers adds.
Normal cortisol levels help to regulate the inflammatory response to keep it in check. Excess chronic levels of cortisol fail to regulate this response.
8. Obesity
Chronic stress leads to “comfort eating,” which often involves the overeating of foods that are high in fat, sugar, and calories. This, in turn, can lead to weight gain. "Chronic stress increases the release of a stress hormone called cortisol, and that seems to increase the amount of fat that's deposited in the abdomen,” Dr. Norris says.
While it's hard to undo our mental association between eating and comfort, trying to comfort eat with healthy veggies and whole grains is always a better move than ice cream and chips.
9. Diabetes
Stress is a potential contributor to chronic hyperglycemia in diabetes. As Dr. Norris describes, “Stress also results in unhealthy eating and drinking that raises the glucose level in people with type 2 diabetes. People who are stressed may have higher levels of certain hormones that can affect how insulin works.”
When you're feeling stressed, your body releases stress hormones, such as cortisol and adrenaline. This should give you an energy boost for a "fight or flight" response. However, the hormones make it harder for insulin to work correctly, a condition known as insulin resistance.
"When stressed, the body prepares itself by ensuring that enough sugar or energy is readily available. Insulin levels fall, glucagon and epinephrine (adrenaline) levels rise, and more glucose is released from the liver," says Dr. Norris. Some people with type 2 diabetes are very sensitive to stress. It causes the body to produce especially high levels of stress hormones, which drive blood sugar levels up.
10. Headaches
Anxiety is known to cause excessive worrying, irritability, and restlessness. Anxiety headaches are another physical symptom that cannot be ignored, as headaches have the power to be debilitating and get in the way of our ability to function.
“Headaches are more likely to occur when you're anxious and stressed. Stress is a common trigger of tension-type headaches and migraines, and can trigger other types of headaches or make them worse,” warns Dr. Norris.
11. Depression and anxiety
Chronic stress is connected with higher rates of depression and anxiety. “Sustained or chronic stress, in particular, leads to elevated hormones such as cortisol, the 'stress hormone,' and reduced serotonin and other neurotransmitters in the brain, including dopamine, which has been linked to depression,” said Dr. Norris.
As depression and anxiety can have extreme results, it's something that needs to be managed by a medical professional, just as any other health problem would be.
12. Gastrointestinal problems
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Sometimes we talk about how anxiety or stress is so severe, it's making us sick to our stomachs. This is actually a real phenomenon!
“Stress may cause a decrease in blood flow and oxygen to the stomach, which could lead to cramping, inflammation, or an imbalance of gut bacteria,” Dr. Norris explains. Furthermore, stress can also worsen gastrointestinal issues, such as chronic heartburn (or gastroesophageal reflux disease, GERD) and irritable bowel syndrome (IBS).
13. Alzheimer's disease
Stress might worsen Alzheimer's Disease, causing its brain lesions to form more quickly. As this is a devastating diagnosis, it's important to avoid the symptoms as long as possible.
Dr. Norris adds, “Some researchers speculate that reducing stress has the potential to slow down the progression of the disease.”
14. Accelerated aging
You know how presidents always look older at the end of their term? Or, how people look visibly older after an illness or a traumatic life event? There's actually evidence that stress can affect how you age.
“People who suffer from chronic stress have chromosomes altered that show the effects of accelerated aging. Stress seems to accelerate aging about 9 to 17 additional years,” says Dr. Norris.
15. Premature death
There are a number of ways chronic stress can kill you, from heart disease to high blood pressure to obesity and so much more. None are very pleasant, and all are avoidable.
”That includes increased levels of cortisol, often referred to as the stress hormone. Elevated cortisol levels interfere with learning and memory, lower immune function and bone density, and increase blood pressure, cholesterol and heart disease. Individuals who perceived that stress affects their health and reported a large amount of stress had an increased risk of premature death,” said Dr. Norris.
Aly Walansky is a NY-based lifestyle writer who focuses on health, wellness, and relationships. Her work appears in dozens of digital and print publications regularly.