Research Says Cheating Can Change Your Brain In Ways That Are More Serious Than Anyone Really Realizes

Last updated on Jun 22, 2026

Cheating changes woman's brain. ahmetyuksek | Pexels
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Wondering if your partner is cheating on you is one of the worst feelings in the world. Sometimes you would rather not know, just to save yourself the heartache. Relationships are hard enough, but having to add on a conversation about infidelity? Yikes, hello, emotional roller coaster.

Many have gone through those hard moments of piecing together that gut-wrenching mystery, wondering whether your loved one is just stressed from a hard day or secretly lying to you with every passing moment.

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It would be so much easier if there were a scientific way to get the truth out. (And one that doesn't just involve guessing, even if there are some red flags to watch out for.) It turns out, scientists hypothesize that people who cheat have identifiably different brain chemistry than people who are faithful to their partners.

The truly tragic way cheating changes your brain, according to research

hopeless young man with his head down and eyes closed Jordan González / Unsplash+

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The study compared brain activity in monogamous and nonmonogamous men 

They showed both sets of men images while scanning their brains with an fMRI machine. As part of the study, the researchers showed each group of men (one group who identified as monogamous, one group identifying as nonmonogamous) romantic and scandalous pictures and recorded which areas of the brain were activated.

When shown romantic images, the brains of monogamous men lit up on the right sides, including their orbitofrontal cortex, which is associated with decision-making. However, the brains of all the subjects of both groups reacted similarly when shown the other images, suggesting that only feelings of romance are changed when a subject identifies as nonmonogamous.

"Results indicated that monogamous men showed more reward-related neural activity when viewing romantic pictures compared to nonmonogamous men," researchers behind the study say. "These results demonstrate that the neural processing of romantic images is different for monogamous and nonmonogamous men."

It's important to note that, as with any scientific study, more research is needed before the underlying hypothesis can be proven, and the study included 20 men, so the size of participation needs to be considered.

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The study also didn't account for polyamorous relationships and didn't ask whether the subjects were cheating

The study only accounted for the fact that nonmonogamous individuals were seeing more than one partner. It would be nice if there were a way to carry an fMRI machine to check for signs of cheating, but that's closer to an episode of Black Mirror than real-life tech. 

Instead, hopefully, open communication will help filter out some of the confusion, and if nothing else, perhaps your instincts can point you in the right direction.

RELATED: I Interviewed More Than 1,600 People To Find Out The Five Core Reasons Men & Women Cheat

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