Could life imitate art?
Ashton Kutcher and Mila Kunis ... Blake Lively and Ryan Reynolds ... Anna Paquin and Stephen Moyer ... Ian Somerhalder and Nina Dobrev ... sometimes you can mix business with pleasure.
These real life Hollywood couples met while playing on-screen love interests and soon blurred the line between fact and fiction—which makes us wonder who else has this-must-be-real chemistry?
More from YourTango: NeNe Leakes On Stripping Past: 'It Became An Addiction'
Here, our top picks for on-screen couples (past and present) that we’d love to see hook up off-screen.
More from YourTango: Trista Sutter Has No Regrets About Post-Pregnancy Plastic Surgery
VIEW THE GALLERY: 4 On-Screen Couples We’d Love to See Together in Real Life
More celebrity couples content from YourTango: