The Social Network
"You are probably going to be a very successful computer person. But you're going to go through life thinking that girls don't like you because you're a nerd. And I want you to know, from the bottom of my heart, that that won't be true. It'll be because you're an asshole."
When Erica Albright (Rooney Mara) breaks up with the borderline autistic Mark Zuckerberg (Jesse Eisenberg) at the beginning of this film, she makes it very clear that his emotional obliviousness is not some cute quirk. A lot of geeky dudes out there really do believe girls simply "don't get me," when in reality they're just frustrated by lack of communication. As Wesley Snipes succinctly stated in White Men Can't Jump: "Listen to the woman."
Oscar-worthy tip: Communication is everything, so try not to get so self-involved.